This is an exciting opportunity to join a cutting-edge Biologics Drug Product Development team, where you'll play a key role in advancing innovative biologic therapies from discovery into clinical development. As a Scientist II, you'll be deeply involved in hands-on lab work-characterizing proteins, evaluating formulation stability, and helping to shape the future of antibody-based treatments including monoclonal antibodies, ADCs, and bispecifics.
If you thrive in a collaborative, science-driven environment and enjoy solving complex challenges in early drug development, this role offers a dynamic and rewarding career path. You'll work alongside a passionate team of experts, contribute to high-impact projects, and support the development of life-changing therapies for patients worldwide.
location: North Chicago, Illinois
job type: Contract
salary: $50.00 - 54.13 per hour
work hours: 9 to 5
education: Bachelors
responsibilities:
- Characterize and assess stability of biologic drug candidates (e.g., monoclonal antibodies, ADCs, bispecifics) using a range of analytical and biophysical techniques.
- Design and execute formulation studies, including screening of excipients and evaluation under various stress conditions (pH, temperature, light, freeze-thaw, etc.) to support development of stable drug products.
- Conduct analytical testing such as HPLC/SEC, electrophoresis (icIEF, SDS-PAGE), mass spectrometry, and differential scanning calorimetry (DSC) for protein characterization.
- Support early-stage developability assessments, including candidate selection and formulation recommendations for clinical studies.
- Document experimental results clearly and accurately in technical reports and present findings to internal stakeholders.
- Collaborate cross-functionally with discovery, analytical, and process R&D teams to align on formulation strategy and development plans.
- Stay current with scientific advancements and contribute to new scientific initiatives within the Biologics Drug Product Development team.
qualifications:
Required Skills (Non-Negotiables):
- Education/Experience:
- BS with 4 years or MS with 2 years of hands-on lab experience (industry preferred)
- Laboratory Skills:
- HPLC/SEC (Size Exclusion Chromatography)
- Electrophoresis techniques (icIEF, SDS-PAGE)
- Mass Spectrometry (MS) for protein characterization
- Protein stability characterization (e.g., DSC)
- Technical Expertise:
- Experience with biologics including monoclonal antibodies, ADCs, bispecifics, trispecifics, and fusion proteins
- Analytical methods: HPLC, UPLC, capillary electrophoresis, particle analysis, UV-vis, DLS, DSC
- Understanding of biologics degradation and stabilization
- Hands-on formulation development (excipient screening, stress testing, high-throughput assays)
- Process Knowledge:
- Familiarity with aseptic manufacturing unit operations: freeze-thaw, compounding/mixing, filtration, filling, lyophilization
- Workstyle:
- Ability to work independently in a fast-paced, lab-focused environment (80% lab, 20% documentation/meetings)
- Strong documentation and scientific communication skills
- Experience with formulation testing and understanding excipient/buffer impact on protein stability
- Strong background in large molecule biologics and protein chemistry
- Ability to manage multiple projects in a matrixed team environment
- Demonstrated adaptability, teamwork, and motivation to learn
- Experience in authoring scientific technical reports and presenting experimental data
skills: CMC, HPLC, GLP (Good Laboratory Practice), GMP (Good Manufacturing Practice)
Equal Opportunity Employer: Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.
At Randstad, we welcome people of all abilities and want to ensure that our hiring and interview process meets the needs of all applicants. If you require a reasonable accommodation to make your application or interview experience a great one, please contact HRsupport@randstadusa.com.
Pay offered to a successful candidate will be based on several factors including the candidate's education, work experience, work location, specific job duties, certifications, etc. In addition, Randstad offers a comprehensive benefits package, including health, an incentive and recognition program, and 401K contribution (all benefits are based on eligibility).
This posting is open for thirty (30) days.
